Pakistan Academy of Sciences

Promoting Science, Technology and Innovation for Socio-economic development

Projects Executed

List of Research Projects from 2003 Onwards

  1. Differentiation of Bone Marrow Stromal cells in aging heart.

Prof. Dr. Sheikh Riazuddin

  1. Unraveling the Genetic architecture of coronary heart Disease in Pakistan Population,

Prof. Dr. Mohammad Perwaiz Iqbal

  1. Role of Exogenous Use of Organic Osmolytes in Enhancing Drought tolerance in Maiz Under greenhouse and field Conditions

Prof. Dr. Muhammad Ashraf

  1. Discovery of Immunomodulatory Natural Products and Understanding the Molecular Basis of their Activity

Prof. Dr. M. Iqbal Choudhary

  1. Use of Halophytic shrubs as Alternative source of Cattle Fodder

Prof. Dr. M. Ajmal Khan

  1. Physiological Studies on Foliar Application of Sodium Antagonistic Essential Mineral Elements to Induce Salt Tolerance in Plants Growing at Saline

Prof. Dr. Rafiq Ahmad

  1. Clinical Trials on Recently Developed Antileishmanial Agents for Cutaneous Leishmaniasis,

Prof. Dr. M. Iqbal Choudhary

  1. Numerical Simulations for Flows Involving Visco-Elastic Fluids,

Prof. Dr. Saleem Asghar

  1. Refinement of Rearing Release Technique of Bracan Hebetor (Say) as a Bio Control Agent for the integrated Management of Armyworm Spodoptera Litura (Noctuidae: Lepidoptera)

Prof. Dr. Muhammad Ashfaq

  1. Evaluation and Standardization of Anti-Urolithic Herbal Preparation,

Prof. Dr. Anwar Waqar

  1. Proteomic Studies in Mangroves under Salinity Stress

Dr. Bilquees Gul

  1. Expression and Characterization of Metallothionein proteins: Multifunctionality of proteins and Post-translational Modification of Carboxyl Group in Proteins

Prof. Dr. A. R. Shakoori

  1. Nutritional, Environmental and Genetic Causes of Hyperhomocysteinemia in Pakistan: Relationship with Premature Coronary Heart Diseases

Prof. Dr. M. Perwaiz Iqbal

  1. Functional Switches in Proteins Regulated by Different Post-Translational Modifications on Amino Group of Proteins: Biochemical, Statistical, computation and Algorithmic Approaches,

Prof. Dr. Nasir ud Din

  1. Synthesis of Potential Anti-tuberculosis analogues based on triterpenoidal and aromatic skeletal

Prof. Dr. Bina Shaheen Siddiqui

  1. Modulation of Activities/ levels of Antioxidants, Vitamins and Osmoprotectants in some prospective summer and winter vegetables due to Salt Stress.

Prof. Dr. Muhammad Ashraf 

  1. The Survey, distribution, Population Dynamics & Biological Control of Mosquito Vector causing Dengue Fever in Karachi.

Prof. Dr. Imtiaz Ahmad

  1. Development of Standardization of Alternative Medical Treatment for Diabetes Mellitus type 2 in an Animal model

Assigned to Dr. Hafiz ur Rahman

  1. Studies on Natural Inhibitor of Kidney Stone Formation and Possible Treatment of Urolithiasis

Prof. Dr. M. Iqbal Choudhary

  1. Microbial Diversity and Molecular Signals Controlling Plant Microbe Interaction in the Rhizosphere

Prof. Dr. Kauser Adbullah Malik

  1. Study of Molecular Genetic Factors Involved in HCV Infection in Pakistan

Prof. Dr. Khaild Mahmood Khan

  1. Screening of Cotton Fiber cDNA Libraries for Eight Gene Families Involved in Fiber Development,

Prof. Dr. Kausar Abdullah Malik

  1. Do single nucleotide Polymorphisms (SNP) in the CC-Chemokine (CCL2 and CC4) determine the severity and or susceptibility of tuberculosis in Pakistan

Prof. Dr. Rabia Hussain

  1. Antioxidant Properties of medicinal Plants from Coastal Areas of Pakistan

Prof. Dr. M. Ajmal Khan

  1. Process Development for the Production of Glucose Oxidase by Aspergilus niger

Prof. Dr. Ikram-ul-Haq

  1. A Sustainable Alternative Fuel from Halophytes

Dr. Bilquees Gul

  1. Genomic and Proteomic Approaches for Kinase-Substrate Specificity Relationship for Phosphoproteins on Hydroxyl Function of Ser/Thr/Tyr to perform Multifunctions: In silicio Studies

Prof. Dr. Nasir-ud-Din

  1. Production of Recombinant Cytokines of Therapeutic Importance.

Prof. Dr. M. Waheed Akhtar

  1. Geology and Geomorphology of the Nagar Parkar Area, District Thar Parkar, Sindh

Prof. Dr. M. Qasim Jan

  1. Phytochemical, Proximate Analysis and Biological Investigation of Some Selected Medicinal Plants of Kurram Agency.

Prof. Dr. Zabta Khan Shinwari

  1. Antibacterial Effect of Ag Nano particles Against Water borne PPathogens.

Prof. Dr. N. M. Butt

  1. Isolation, Structure Elucidation and Biological Activity Studies of the Medicinal Plants of Pakistan belonging to genera Asttragallus and Gaillonia

Prof. Dr. Viqar Uddin Ahmad

  1. Biosystematic, Eco-Biology and Management of Dusky Cotton Bug as a growing threat for Cotton Crop in Punjab, Pakistan”

Prof. Dr. Muhammad Ashfaq

  1. Study of Molecular Structure and Drugability potential of New Inhibitors of β-Glucuronidase by Single Crystal X-ray Diffraction and NMR Spectroscopy Techniques.

Prof. Dr. Atta-ur-Rahman

  1. Genetic Analysis of Retinilis Pigmentosa in Pakistani Population.

Prof. Dr. Raheel Qamar

  1. Studies on Pharmacological Activities of Selected Nuts in Transgenic and Aluminum-Induced Alzheimer’s Disease Mice.

Prof. Dr. Anwarul Hasan Gilani

  1. Biology-Oriented Synthesis (BIOS)” Based Synthesis of Libraries of Santonin”

Prof. Dr. G. A. Miana

  1. Use of Single Nucleotide Polymorphisms as a Tool to Study the Response Towards Interferon Therapy in Hepatitis C Patients.

Prof. Dr. Khalid Mahmood Khan

  1. Role of Amino Group Modifications (Posttranslationally and Co-transalationally) on multi-Functional Relationship of Proteins,

Prof. Dr. Nasir uddin

  1. Development of Standardization of Alternative Medical Treatment for Diabetic etc,

Prof. Dr. Muhammad Anwar Waqar

  1. Investigations on Growth and Development of some oil Yielding Indigenous Plants of Arid/ Saline Marginal Land and looking into their Capability of Producing Bio Diesel for Commercial Consumption,

Prof. Dr. Muhammad Rafiq

  1. Field Studies of Transgenic Cotton

Prof. Dr. Mehbub Ali

  1. Appraisal of Nutritional and Antioxidative Status of Some Important Pulse Grown Under Salinity and Drought Stress

Prof. Dr. M. Ashraf

  1. Studies on reverting Insulin Resistance (IGT and IFG) by Employing Natural Products for the Prevention of the On-set of Metabolic Syndrome

Prof. Dr. M. Iqbal Choudhary

  1. Biology Oriented Parallel synthesis (BIOPs): Synthetic Transformations on Nitroimidazoles in Search of Better Therapeutic Agent.

Prof. Dr. Khalid Mohammad Khan

  1. Laser induced Plasma Spectroscopic Studies of Materials”.

Prof. Dr. Aslam Baig

  1. Genetic Association Studies of Bladder Cancer Patients.

Prof. Dr. Raheel Qamar

  1. Studies of Structural and Molecular Mechanism of Resistance Reversal in Staphylococcus aureus by Natural Products

Prof. Dr. M. Iqbal Choudhary

  1. Molecular Characterization and Screening of Bacteria Isolated from Plant Rhizosphere for Plant Growth Promoting Properties

Prof. Dr. Kauser A. Malik

  1. Metabolic and Inflammatory Markers in Children with Severe Obesity

Prof. Dr. M. Arslan

  1. Endophytes of Invasive and Stress Resistant Plants as an Alternative Means of Growth Promotion and Yield Enhancement of Major Crops

Prof. Dr. Zabta Khan Shinwari

  1. Antibacterial Constituents from Indigenous Medicinal Plants

Prof. Dr. Bina S. Siddiqui

  1. Antibacterial Effect of Zinc Oxide Nanoparticles on Local Waterborne Bacterial Strains and its Feasibility Study for Production of Cheap Drinking Water Filter

Prof. Dr. N. M. Butt

  1. Fabrication, structural, electrical and dielectric properties of soft nanoferrites

Prof. Dr. Asghari Maqsood

  1. Green Combination: blockade for hypertension and cardiac dysrythmia

Prof. Dr. Khalid Mahmood Khan

  1. Molecular Basis of Blindness due to Cataract in Pakistani Population

Prof. Dr. Sheikh Riazuddin

  1. Investigation of Genetic Basis of Human Hair Loss

Prof. Dr. Wasim Ahmad

  1. Incidence of Leptin and Melanocortin 4 receptor Gene Mutations and Metabolic Profile in Subjects with Early Onset Severe Obesity.

Prof. Dr. M. Arslan

  1. Identification of Common Genetic Factors in Age Related Multifactorial Eye Diseases

Prof. Dr. Raheel Qamar

  1. Laser Assisted Mass Spectroscopic Studies of Materials

Prof. Dr. M. Aslam Baig

  1. Functional Importance of O-GlcNAc Modification of Merozoite Surface Proteins of P. falciparum as Potential Vaccine Candidate: In silico approach

Prof. Dr. Nasir Uddin

  1. Enhancement in Cotton Production and Quality under Climate Change Scenario of Multan Using Novel Growth Promoting Substances

Prof. Dr. M. Ashraf

  1. Exploring Plant Growth Promoting Potential of Halotolerant Bacteria

Prof. Dr. Zabta Khan Shinwari

  1. Isolation, Molecular Identification and Control of Endophytic Contaminants in In Vitro Cultures of Fagonia indica

Dr. Bilal Haider Abbasi (Member)

  1. Body iron Status and risk of type II diabetes mellitus in a Pakistani population

Prof. Dr. M. Perwaiz Iqbal

  1. Theoretical Study of Space Plasma having Inhomogeneous Flows

Prof. Dr. Hamid Saleem

  1. Biology-Oriented Synthesis (BIOS)Based Synthesis of Libraries of Steroids

Prof. Dr. G. A. Miana

  1. Stability Analysis and some interesting Cosmic Issues

Prof. Dr. M. Sharif

  1. Osteogenic Potential of a Local Herb Cissus quadrangularis : Development of Potential Drug for Osteoporosis

Prof. Dr. A.R. Shakoori

  1. Targeting central Nervous System for novel therapeutic Effects of Metfornin.

Prof. Dr. Darakhshan Jabeen Haleem

  1. Synthesis and Characterization of a disulfide crosss-linked multifunctional in situ gelling cargo for oral peptide drug delivery

Dr. Gul Shahnaz (Member PAS)

  1. Synthesis of bioactive guanidine based surfactants and their application as anticancer, antibiotic and as a drug delivery agent

Prof. Dr. Amin Badshah

  1. Molecular Characterization of Glu-1, Glu-3 and wbm loci in D-genome synthetic hexaploid wheats and their advanced derivatives

Dr. Tariq Mahmood (Member PAS)

  1. Identification and characterization of different proteins involved in osmoregulation of halophilic bacteria through culturable and metaproteomics approaches

Prof. Dr. Kauser A. Malik

  1. Production of Keratinase Enzyme for Deharing Process in Leather Industry

Prof. Dr. Ikram-ul-Haq

  1. Anticancer and Antidiabetic Drug Discovery from Medicinal Plants in Pakistan: From Bench to Bedside                                                                                                                                                           

Prof. Dr. Zabta Khan Shinwari

  1. Cost Effective Synthesis of New Environmental Friendly Surfactants and their Application as Drug Carrier

Prof. Dr. Saqib Ali

  1. Shear Flow-Driven Instabilities and Nonlinear Waves in Multi-Component Space Plasmas

Prof. Dr. Hamid Saleem

  1. “Enhancement in Detection Limit of Trace Elements Using Dual Pulse Laser Breakdown Spectroscopy.”

Prof. Dr. M. Aslam Baig

  1. “Designing fusion antigens for diagnostic and prophylactic applications in tuberculosis”

Prof. Dr. Waheed Akhtar

  1. Discovery of Anti-biofilm Agents against Multi-drug Resistance Staphylococcus aureus as Potential New Antibiotics and Study of their Mechanism of Action.”

Prof.  Dr. Atta-ur-Rahman

  1. “Study of therapeutic targeting of tumor necrosis factor alpha in lymphocytes using Nano particles for limiting cardiovascular disease”.

Prof. Dr. N. M. Butt

  1. Association of Bone Metabolic Characteristics and Endocrine and Inflammatory Markers, with Severe Obesity in Children and Adolescents.”

Prof. Dr. M. Arslan

  1. Effect of Advanced Glycation Endproducts on a Pakistani Breast Cancer Cell line BC-PAK-1: Link between Diabetes and Breast Cancer.”

Prof. Dr. M. Iqbal Choudhary

  1. “Design Synthesis, α-Amylase and α-Glucosidase Inhibition Study of Pyridine Derivatives for the Treatment of Diabetes Complications and Other Pathologies.”

Prof. Dr. Khalid M. Khan

  1. “Understanding the Progression of Heart Failure in Ischemic Heart Disease Patients using Metabolomics tool”.

Dr. Syed Ghulam Musharaf, Member PAS

  1. Relation of ABO genotypes and soluble adhesion molecules with myocardial infarction in Pakistani population and methylation status of ABO gene promoter in this disease

Prof. Dr. M. Pervaiz Iqbal

  1. Systematic Screening of Environment Friendly Biodiesel from Non-Edible Oil Yielding Plants

Dr. Mushtaq Ahmad (Member PAS)

  1. Mapping Genes Involved in Familial Infertility

Prof. Dr. Wasim Ahmad

  1. Comparative Assessment of Biological Potential of some Novel Medicinal Plants of Gilgit-Baltistan

Dr. Tariq Mahmood (Member PAS)

  1. Microbiome profiling of the cotton plant under Cotton Leaf Curl Disease attack

Prof. Dr. Kauser A. Malik

  1. Potential anti-inflammatory agents from local medicinal plants for treatment of inflammation associated with various diseases

Prof. Dr. Bina Shaheen Siddiqui

  1. Facile preparation of binder free Prussian blue analogue based electrodes for enchased water oxidation activity.

Prof. Dr. Saqib Ali

  1. Anti-adipogenic potential of Cissus quadrangularis: Molecular Evidence

Prof. Dr. A. R. Shakoori

  1. Biosynthesis of recombinant laccase from bacterial source for textile industry and waste water treatment.

Prof. Dr. Ikram ul Haq

  1. Heteropolyacids immobilized on mesoporous silica as heterogeneous catalysts for one-step transesterification process of low cost triglycerides and related feedstock

Prof. Dr. Amin Badshah

  1. Molecular Understanding of Fluorosis using Metabolomics-Mass Spectrometry Approach

Dr. Syed Ghulam Musharaf (Member PAS)

  1. Mechanism for synergic removal of antibiotic and ARG in livestock wastewater using laccase immobilized by composited/modified graphene oxide materials

Dr. M. Zaffar Hashmi (Member PAS)

  1. To determine the Genetic Risk Factors for Stroke and Database establishment for personalized Medicine in Pakistan

Prof. Dr. Azra Khanum

  1. Physical Viability and Stability of some Cosmological Models in Modified Gravity

Prof. Dr. M. Sharif

  1. Development of a reliable, cost-effective and high throughput serodiagnosis method for tuberculosis

Prof. Dr. M. Waheed Akhtar

  1. CNTs encapsulated FeIII/II-CeIV and FeIII/II-InIII based Prussian Blue analogues as electrode materials for rechargeable ion batteries

Dr. Ali Haider (Member PAS)

  1. Nutraceutical Analysis of Precious wild edible Fruits Diversity in Lesser Himalayas Pakistan

Dr. Mushtaq Ahmad (Member PAS)

  1. Petrographic and Petrologic studies in Kohistan magmatic arc (northern Pakistan) and Nagar Parkar igneous complex (southeastern Pakistan)

Prof. Dr. M. Qasim Jan

  1. Nonlinear modeling of Nano fluids with entropy generation

Prof. Dr. Tasawar Hayat

  1. Oxidative Stress in Severely Obese Children and its Impact on Metabolic Dysfunction

Prof. Dr. M. Arslan

  1. Fabrication of glucose sensor based on Metal Organic Frameworks interconnected by CNTs and decorated with metallic nanoparticles.

Prof. Dr. M. Aslam Baig

 

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